The ASAH2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASAH2. This antibody recognizes Human, Mouse, and Rat antigen. The ASAH2 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816])